Poly-L-lactic acid (PLLA)

A substance used in collagen-stimulating fillers and some facial lifting threads. It is broken down in the body over time but cannot be dissolved with the enzyme hyaluronidase. In a review of granulomas linked to this group, a large proportion of cases were associated with poly-L-lactic acid and calcium hydroxylapatite.

Articles that mention this term

Treatment GuidesCollagen-Stimulating Fillers: How Do They Differ from Hyaluronic Acid, Who Are They For, and What Are the Risks?How collagen-stimulating fillers (poly-L-lactic acid, calcium hydroxylapatite, polycaprolactone) work, why they cannot be dissolved, and nodule risk.Reviewed by the Medical Aesthetics Expert Board Safety CentreLumps, Granulomas and Vascular Occlusion after Collagen FillersLumps, granulomas and vascular occlusion after poly-L-lactic acid, calcium hydroxylapatite, polycaprolactone: telling them apart, emergency signs.Reviewed by the Medical Aesthetics Expert Board Treatment GuidesThread Lift (Non-Surgical Facial Lifting Threads): Who Is It For, How Long Does It Last, and What Are the Risks?What a thread lift is, who it suits, how long it lasts: limits of dissolvable threads, possible side effects and a realistic comparison with surgery.Reviewed by the Medical Aesthetics Expert Board Treatment GuidesSkin Booster Injections: What Are They, and Who Are They For?What is a skin booster and how does it differ from filler? Hydrating injections, biostimulators, exosomes, polynucleotides: evidence, risks, expectations.Reviewed by the Medical Aesthetics Expert Board Safety CentreComplications of Permanent and Semi-Permanent Fillers: Silicone, Granulomas, Late Reactions and TreatmentPermanent and semi-permanent filler complications: why granulomas, migration and infection appear years later with fillers like silicone, and treatment.Reviewed by the Medical Aesthetics Expert Board Treatment GuidesDissolving Filler (Hyaluronidase): When Is It Needed, How Is It Done, and What Should You Watch Out For?Dissolving filler with hyaluronidase: when it is needed, which fillers it works on, allergy risk and skin testing, sessions, and having filler again.Reviewed by the Medical Aesthetics Expert Board

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