TürkiyeDiagnosis and screening
2,243 children with low ALP levels screened in Ankara: hypophosphatasia found in 16
A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.
At Ankara Bilkent City Hospital, 2,243 children with low ALP levels were studied. In most of them, the low level was temporary. A persistently low level was present in 103 children. Of these, 16 were diagnosed with hypophosphatasia. The most common finding was short stature.
What does it mean for patients and families?
A persistently low ALP level in the blood may be the first clue to this easily overlooked disease. If the level comes back low, talking to a doctor can speed up diagnosis.
Source
Scientific paper: Evaluation of Low Alkaline Phosphatase Levels in Clinical Practice: Implications for Diagnosing Hypophosphatasia. Calcified Tissue International, 2025. DOI: 10.1007/s00223-025-01424-3 · PubMed 40828320
The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).
This page is translated from the Turkish original.
Related disease: Hypophosphatasia (HPP)
This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.