TürkiyeResearch and clinical trials
9 centers in the Marmara region: stroke-like episodes studied in children with mitochondrial disease
A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.
In the Marmara Region, 9 pediatric metabolic centers studied children with mitochondrial disease. Of 34 children with a genetic diagnosis, 13 had had stroke-like episodes. These episodes were seen most often in MELAS and POLG disease. Brain MRI findings did not match the distribution of blood vessels. In MELAS, improvement was seen in children started on arginine during an episode.
What does it mean for patients and families?
Sudden neurological symptoms in a child with mitochondrial disease require emergency evaluation. This is a small, retrospective study; treatment decisions are made with the doctor.
Source
Scientific paper: Profiles of paediatric patients experiencing stroke-like episodes associated with mitochondrial disease. Frontiers in Neurology, 2025. DOI: 10.3389/fneur.2025.1657852 · PubMed 41438888
The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).
This page is translated from the Turkish original.
Related disease: MELAS syndrome
This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.