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Medical AestheticsTreatment GuidesStart With a ConcernSafety CentreGuidesRumour or Science?GlossaryToolsAsk an ExpertExpert Board
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Skin Care and Medical Aesthetics in Your 40s: Volume, Elasticity and Realistic Expectations

In your 40s, skin changes begin to show not only on the surface but also in the deeper layers of the skin, in the fat tissue and in the bone structure. This is why expecting a single product or a single procedure to solve everything is not realistic. This guide explains what happens at this stage, which approaches can be discussed and how you can keep your expectations balanced.

Reviewed by the Medical Aesthetics Expert BoardReview date: 5 October 2026~5 min

What is happening in your skin in your 40s?

With age, the collagen and elastic fibres in the skin decrease, the skin becomes thinner and begins to lose its elasticity. At the same time, the fat tissue in the face shifts and decreases in some areas, and slow changes also take place in the bone structure that supports the face. The combination of these changes can lead to hollowing under the eyes, more visible lines running from the side of the nose to the corner of the mouth, and softening of the jawline.

Sun damage accumulated over the years also becomes more visible at this stage: sun spots, uneven skin tone and fine wrinkles may increase. In women, towards the end of their 40s, hormonal changes associated with the years before menopause may also begin to affect the skin.

The role of skin care: the basics still apply

Before talking about procedures, it is important to know this: sun protection and regular skin care are still the most basic steps at this age. No procedure gives a lasting improvement in skin that is not protected from the sun.

  • Use a broad-spectrum sunscreen every day.
  • If your skin is becoming drier, it may help to switch to a richer moisturiser.
  • Retinoids are among the most researched skin care ingredients for fine lines and skin texture related to sun damage; because the skin may be more sensitive at this age, it is advisable to start them with care.
  • Smoking is one of the main factors that speed up skin ageing.

You can find the basics about retinoids and sun protection in our article “Skin Care and Medical Aesthetics in Your 30s”.

Different problems, different methods

Because the changes seen in your 40s take place in different layers, each may call for a different approach. The table below gives a general framework; which method suits you can only be decided after an examination.

ChangeApproaches that can be discussedNote
Lines caused by facial expressions (forehead, between the eyebrows, corners of the eyes)Botulinum toxinThe effect is temporary; regular repeat treatment is needed
Volume loss, hollowingHyaluronic acid fillerMeasured use is important to preserve natural proportions
Skin texture, fine wrinkles, pigment spotsChemical peels, fractional laser, skin care productsRecovery time varies with the method
Mild sagging, loss of elasticityEnergy-based methods such as radiofrequency and HIFUThe effect is limited; with significant sagging, a surgical assessment may be needed

You can find detailed information on each of these methods in our related articles; for example, our articles “Hyaluronic Acid Filler” and “Radiofrequency Skin Tightening and Radiofrequency Microneedling” explain what these methods can and cannot do.

In your forties, change does not come from a single cause; volume, elasticity and skin quality should be assessed together. A realistic plan means looking at the face as a whole instead of expecting everything from a single procedure.

Dr. Hamza GemiciDr. Hamza Gemici
Medical Director, DoktorClub · Aesthetic Medicine Physician

What does a combined approach mean?

At this age, physicians may often discuss, instead of a single procedure, several methods targeting different problems, applied within a plan and spread out over time. For example, expression lines, volume loss and skin texture may each be addressed separately.

  • A combined approach does not mean having many procedures on the same day. Which procedures are done, in which order and at what intervals is planned by the physician.
  • Each additional procedure brings its own risk and recovery time.
  • The plan should be made according to your priorities. It is possible to start with what bothers you most and decide whether to continue after seeing the result.
  • Do not hesitate to ask about the reasoning behind a plan offered to you, its alternatives and the consequences of doing nothing.

Be cautious about plans that suggest many procedures in a short time or are offered as a package. A plan should be presented by giving you time to think, not by putting pressure on you.

Realistic expectations

Medical aesthetic procedures can soften certain changes and help your skin look more rested. However, they do not stop ageing and do not turn your face back by years.

  • The effect of non-surgical procedures is mostly temporary, and repeat treatment is needed to maintain it.
  • The effect of energy-based skin tightening methods is generally mild to moderate and varies from person to person.
  • With significant sagging, the effect of non-surgical methods is limited; in this case, a plastic surgeon’s opinion may be needed.
  • Too much filler or too frequent treatment can lead to an unnatural look in the face. Less often looks more natural.
  • Results vary with skin quality, lifestyle habits and genetic make-up.

If you are considering a procedure, review your health first

In your 40s, the number of regularly used medicines and chronic diseases may increase. At the examination, it is important to tell your physician about:

  • Blood-thinning medicines, aspirin and some painkillers, and herbal supplements (these can increase the risk of bruising; do not stop these medicines on your own)
  • Health problems such as diabetes, autoimmune diseases and bleeding disorders
  • Fillers, threads or surgical procedures you have had before
  • A history of cold sores (some procedures can trigger cold sores)
  • Allergies and problems experienced with previous procedures

⚠See a dermatologist without delay in these situations

  • A new mole or spot, or one that changes in size, shape or colour
  • A sore that bleeds, crusts or does not heal within a few weeks
  • A bump on the skin that keeps growing, looks shiny or is scaly

Final word

Your 40s may be a time when you strike a balance between accepting the changes in your skin and improving them. Whichever path you choose, sun protection and regular skin care are fundamental. If you are considering a procedure, it is advisable to decide with a physician with whom you can openly discuss your expectations and who, when appropriate, can tell you that a procedure is not necessary for you. When choosing a physician, you can use our article “A 10-Point Safety Checklist for Choosing a Clinic and Physician for Medical Aesthetics”.

Questions to ask your physician

  1. Which of the changes in my face come from volume loss, and which from skin quality?
  2. Which problem is the priority for me, and where does it make sense to start?
  3. Which procedures are in the plan you are suggesting, and why in this order?
  4. How long does the effect of each of these procedures last, and will repeat treatment be needed?
  5. In my case, are non-surgical methods enough, or should I get a surgical opinion?
  6. Do the medicines and supplements I take affect my risk with the procedure?
  7. What happens if I do not have any procedure?

Frequently asked questions

In your 40s, is filler or botulinum toxin (commonly called “botox”) more suitable?

These two target different problems. Botulinum toxin targets lines caused by facial expressions, while hyaluronic acid filler targets volume loss. Whether one of them, or both, is suitable for you is decided after an examination.

Do skin tightening procedures replace a facelift?

No. Energy-based skin tightening methods can give a limited improvement in mild sagging; however, with significant sagging they do not replace surgery. A plastic surgeon’s opinion on this may be helpful.

Can I have more than one procedure on the same day?

Some procedures can be done in the same session, while others require an interval. Your physician plans this according to the type of procedures and your situation.

How long do the effects of procedures last?

This varies with the method and the person. The effect of non-surgical procedures is mostly temporary, and repeat treatment is needed to maintain it. You can ask your physician about the expected duration before the procedure.

I take a blood thinner; can I have a procedure?

Blood-thinning medicines can increase the risk of bruising and bleeding. Do not stop these medicines on your own; you need to talk both to the physician who prescribed the medicine and to the physician who will perform the procedure.

Sources

  1. Before you have a cosmetic procedure — NHS
  2. Is a cosmetic procedure right for me? — NHS
  3. Botulinum toxin therapy: Overview — American Academy of Dermatology (AAD)
  4. Dermal Fillers (Soft Tissue Fillers) — U.S. Food and Drug Administration (FDA)
  5. Sunscreen and sun safety — NHS (United Kingdom)
  6. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety (Mukherjee S et al.). Clin Interv Aging 1(4):327–348 — Clinical Interventions in Aging, 2006

Medical Aesthetics Expert Board

This article has been reviewed by the DoktorClub Medical Aesthetics Expert Board.

  • Dr. Hamza GemiciDr. Hamza Gemici
    Medical Director, DoktorClub · Aesthetic Medicine Physician
  • Dr. Murat ToktamışoğluDr. Murat Toktamışoğlu
    Physician · Aesthetic Medicine
  • Prof. Dr. Hasan Ahmet ÖzdoğanProf. Dr. Hasan Ahmet Özdoğan
    Professor of Otorhinolaryngology and Head & Neck Surgery
← Previous articleSkin Care and Medical Aesthetics in Your 30sNext article →Skin Care and Medical Aesthetics at 50 and Beyond

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GuidesA Guide for First-Time Medical Aesthetic PatientsGuidesMedical Aesthetics for Men: What Is Different, and What Should You Watch Out For?GuidesAftercare Following Medical Aesthetic Procedures: General Principles and Warning Signs

At a glance

At this stage
Volume loss, reduced elasticity, more visible lines and pigment spots
The basics
Sun protection and regular skin care are still the most important steps
Procedures
Different methods for different problems; a combined plan is often discussed
Expectations
Procedures improve, they do not stop time; effects are mostly temporary
First
An examination and a review of your medical history and medicines

In this article

  1. What is happening in your skin in your 40s?
  2. The role of skin care: the basics still apply
  3. Different problems, different methods
  4. What does a combined approach mean?
  5. Realistic expectations
  6. If you are considering a procedure, review your health first
  7. Final word
Safety Centre

This content is for information only and does not replace an examination or medical assessment. Ask your physician about your own situation.

This section contains no advertising, sponsored content or prices. Editorial Principles