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TürkiyeResearch and clinical trials

72 Hirschsprung operations in Konya: botulinum injection helped most children with recurrent bowel inflammation

Peer-reviewed publication

A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.

In Konya, 72 Hirschsprung patients operated on between 2011–2023 were studied. Most problems were seen in children with long-segment involvement. The frequency of bowel inflammation did not differ between surgical methods. For recurrent inflammation, 13 children received botulinum toxin injections into the anal sphincter. Episodes decreased in 11 of them.

What does it mean for patients and families?

Bowel inflammation can continue after surgery; additional treatments may help some children. This is a small, retrospective study. The choice of treatment should be discussed with the surgeon.

Source

PubMed (Journal of Clinical Medicine): Surgical Complications in Hirschsprung Disease and the Impact of Botulinum Toxin Injection on Hirschsprung-Associated Enterocolitis.

Scientific paper: Surgical Complications in Hirschsprung Disease and the Impact of Botulinum Toxin Injection on Hirschsprung-Associated Enterocolitis. Journal of Clinical Medicine, 2026. DOI: 10.3390/jcm15041665 · PubMed 41753351

The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).

This page is translated from the Turkish original.

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This page was translated from Turkish by the Doktorclub editorial team.