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In Kennedy disease, muscle MRI tracked muscle loss better than walking tests

Peer-reviewed publication

A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.

A total of 26 adults with Kennedy disease were followed with whole-body muscle MRI every six months for up to 18 months. Within one year, muscle volume decreased and the proportion of fat in the muscles increased. This change was similar and steady in every patient. MRI proved more sensitive than walking and daily function tests.

What does it mean for patients and families?

This is not a treatment, but a study of a measurement method. It may help future drug trials see an effect in a shorter time.

Source

PubMed (Neurology): Muscle MRI as an Imaging Biomarker of Muscle Damage in Patients With Spinal and Bulbar Muscular Atrophy.

Scientific paper: Muscle MRI as an Imaging Biomarker of Muscle Damage in Patients With Spinal and Bulbar Muscular Atrophy. Neurology, 2026. DOI: 10.1212/WNL.0000000000218309 · PubMed 42479997

The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).

This page is translated from the Turkish original.

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This page was translated from Turkish by the Doktorclub editorial team.