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130 PAP patients from Greece, Türkiye and Cyprus: inhaled GM-CSF alone also found effective

Peer-reviewed publication

A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.

The 20-year records of 130 PAP patients from three countries were compared. 87 of the patients were from Türkiye. Whole lung lavage was used more often in Türkiye, and inhaled GM-CSF more often in Greece. All treatments were found to be effective. Response to treatment was lower in patients who developed lung fibrosis.

What does it mean for patients and families?

Inhaled GM-CSF may be an alternative to whole lung lavage. Diagnosis and treatment before fibrosis develops appear to be important. This is a retrospective comparison.

Source

PubMed (Respirology): Pulmonary Alveolar Proteinosis in Greece-Türkiye-Cyprus: Answers in a Real-Life Comparison.

Scientific paper: Pulmonary Alveolar Proteinosis in Greece-Türkiye-Cyprus: Answers in a Real-Life Comparison. Respirology, 2026. DOI: 10.1002/resp.70288 · PubMed 42457194

The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).

This page is translated from the Turkish original.

This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.

The information on these pages is for general information only and does not replace medical advice. Talk to your doctor about diagnosis and treatment decisions. In an emergency in Türkiye, call 112.

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This page was translated from Turkish by the Doktorclub editorial team.