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TürkiyeResearch and clinical trials

252 Takayasu patients from 11 centers in Türkiye: aortic valve leakage found in one third

Peer-reviewed publication

A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.

A total of 252 Takayasu patients from 11 rheumatology centers in Türkiye were studied. 33% of patients had aortic valve leakage. In 12%, the leakage was moderate or severe. 7% needed valve replacement. During a median follow-up of 8 years, the leakage increased in some patients, but it did not affect death or flare rates.

What does it mean for patients and families?

In Takayasu, the heart valves may also need regular monitoring. This finding supports heart and rheumatology doctors working together. This is a retrospective study.

Source

PubMed (Frontiers in Immunology): Long-term outcomes of aortic valve insufficiency in patients with Takayasu arteritis.

Scientific paper: Long-term outcomes of aortic valve insufficiency in patients with Takayasu arteritis. Frontiers in Immunology, 2025. DOI: 10.3389/fimmu.2025.1667603 · PubMed 41058700

The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).

This page is translated from the Turkish original.

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This page was translated from Turkish by the Doktorclub editorial team.