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USAResearch and clinical trials

Bevacizumab in NF2: greater shrinkage seen in nerve tumors other than those of the hearing nerve

Peer-reviewed publication

A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.

In the USA, bevacizumab was given for two years to patients with NF2. This analysis looked at tumors of the brain's lining (meningiomas) and other nerve tumors. Of the nerve tumors, 42% shrank. For tumors of the brain's lining, this rate was only 13%. More than half of the tumors of the brain's lining grew.

What does it mean for patients and families?

The drug may not have the same effect on every tumor type. This is a small, retrospective analysis. Treatment decisions are made with the doctor.

Source

PubMed (Journal of Neuro-Oncology): Effect of bevacizumab on non-target intracranial meningiomas and non-vestibular schwannomas in NF2-related schwannomatosis: NF104.

Scientific paper: Effect of bevacizumab on non-target intracranial meningiomas and non-vestibular schwannomas in NF2-related schwannomatosis: NF104. Journal of Neuro-oncology, 2025. DOI: 10.1007/s11060-025-05020-1 · PubMed 40434540

The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).

This page is translated from the Turkish original.

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This page was translated from Turkish by the Doktorclub editorial team.