TürkiyeResearch and clinical trials
Choline supplementation lowered homocysteine in classical homocystinuria: a small study from Istanbul
A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.
Istanbul University gave choline for 8 weeks to 15 patients whose homocysteine remained high despite treatment. All participants had a low dietary choline intake. Average homocysteine fell from 123 to 61 µmol/L. Of the 4 patients with fatty liver, the fatty liver improved in 3.
What does it mean for patients and families?
This is a small, short study. Do not start choline supplements on your own. Ask your metabolic disease doctor and your dietitian about this.
Source
Scientific paper: Choline supplementation in classic homocystinuria: impact on homocysteine and hepatic steatosis. Pediatric Research, 2026. DOI: 10.1038/s41390-025-04383-5 · PubMed 40987823
The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).
This page is translated from the Turkish original.
Related disease: Classic homocystinuria (CBS deficiency)
This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.