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TürkiyeResearch and clinical trials

Diet and gut flora studied together in 8 patients with methylmalonic acidemia in Ankara

Peer-reviewed publication

A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.

At Ankara University, 8 patients with methylmalonic acidemia were followed step by step. When the share of natural protein in the diet was increased, harmful substances in the urine decreased. A short course of antibiotics given afterward lowered these substances somewhat further. Meanwhile, the diversity of the gut flora decreased.

What does it mean for patients and families?

This is a small preliminary study, not a treatment recommendation. Do not change diet or medicines on your own. Every change should be discussed with the metabolic team.

Source

PubMed (Journal of Inherited Metabolic Disease): Dietary Protein Modulation, Gut Microbiota, and Metabolic Control in Methylmalonic Acidemia: A Prospective Longitudinal Study.

Scientific paper: Dietary Protein Modulation, Gut Microbiota, and Metabolic Control in Methylmalonic Acidemia: A Prospective Longitudinal Study. Journal of Inherited Metabolic Disease, 2026. DOI: 10.1002/jimd.70172 · PubMed 41806138

The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).

This page is translated from the Turkish original.

This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.

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This page was translated from Turkish by the Doktorclub editorial team.