TürkiyeResearch and clinical trials
Long-term follow-up of 491 children with retinoblastoma at Hacettepe: 13 developed a second cancer
A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.
Hacettepe University reviewed 491 children with retinoblastoma it had followed over 51 years. Years later, 13 of these children developed a second cancer. In nine of them, the disease was the hereditary type. The most common second cancer was bone cancer. The five-year survival rate for the whole group was 91%.
What does it mean for patients and families?
It is important for people with hereditary retinoblastoma to be followed for many years even after treatment. The follow-up plan is made together with eye and pediatric cancer doctors. This is a single-center, retrospective study.
Source
Scientific paper: Second Malignant Neoplasms in Long-term Retinoblastoma Survivors: Retrospective Cohort Study of 491 Patients in Turkey. Journal of Pediatric Hematology/oncology, 2025. DOI: 10.1097/MPH.0000000000003039 · PubMed 40262045
The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).
This page is translated from the Turkish original.
Related disease: Retinoblastoma
This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.