TürkiyeResearch and clinical trials
Low bone density found in 39.5% of 76 patients with severe congenital neutropenia in Türkiye
A study published in a journal and reviewed by independent scientists. Even so, a single study is not conclusive; it needs to be replicated.
In Türkiye, 76 patients at 6 centers were studied. In 75% of patients, the mother and father were related. The most common cause was the HAX1 gene, seen in 46 patients. On bone measurement, density was low in 39.5% of patients. Osteoporosis (bone loss) was present in 29.7% of adults. No link was found between the G-CSF dose and bone loss.
What does it mean for patients and families?
Bone health should also be monitored in this disease. You can ask your doctor about a bone density measurement. The cause of the bone loss is not yet clear.
Source
Scientific paper: Evaluation of bone mineral density in patients with severe congenital neutropenia: experience of six centers in Turkey. Scientific Reports, 2026. DOI: 10.1038/s41598-026-52473-z · PubMed 42178347
The source page was opened and read on October 7, 2026. Summary prepared by the Doktorclub editorial team and translated from Turkish; it has not yet been reviewed by a physician (a scientific board is being set up).
This page is translated from the Turkish original.
Related disease: Severe congenital neutropenia (SCN)
This page reports a development; it is not a treatment recommendation. Your doctor decides whether a treatment is right for you.